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What is Avanafil?

Avanafil, also known as Strendra, is a prescription medication recognized for its role in treating erectile dysfunction (ED) in men. Belonging to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors, Avanafil works by increasing blood flow to the penis to help a man get and keep an erection. Its fast-acting nature makes it a preferred choice for those seeking a quicker onset of action compared to some other ED medications.

Avanafil Uses

The primary use of Avanafil (Strendra) is to treat erectile dysfunction. This condition can affect men of all ages but is more common in older men. Erectile dysfunction is characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Avanafil is designed for men who have been diagnosed with ED and need assistance to improve their sexual function.

Working of Avanafil

This salt works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). Normally, PDE5 breaks down a substance called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels and allows blood to fill the penile tissues, leading to an erection. By blocking PDE5, the Avanafil pill increases the levels of cGMP within the penile tissues, enhancing blood flow and enabling an erection to occur when combined with sexual stimulation. This mechanism makes it effective in treating the symptoms of erectile dysfunction.

Avanafil Dosage

The dosage of Avanafil should be strictly followed as prescribed by a healthcare professional. It is typically taken as needed, about 30 minutes before sexual activity. The starting dose is often 100 mg, but it can be adjusted based on the individual’s response and tolerability. It’s important not to take more than one dose per day. Adjustments may be made for men who experience side effects or those who take certain other medications.

Side Effects

Like any medication, Avanafil can cause side effects, although not everyone experiences them. Common side effects include headaches, flushing, nasal congestion, back pain, and an upset stomach. These are generally mild and temporary. However, there are more serious side effects to be aware of, such as changes in vision, hearing loss, or an erection lasting more than four hours (priapism), which requires immediate medical attention.


Before taking Avanafil, it’s important to inform your healthcare provider about your medical history, especially if you have heart problems, high or low blood pressure, severe liver or kidney disease, or if you are at risk of stroke. It should not be used by women or children. Men who are advised against sexual activity due to health issues should not take Avanafil tablets.


Avanafil can interact with several other medications, potentially leading to adverse effects. It should not be used with nitrates (used for chest pain) or guanylate cyclase stimulators (for pulmonary hypertension), as this can cause a dangerous drop in blood pressure. Also, inform your doctor about all medications you are taking, including over-the-counter drugs and herbal supplements, to avoid harmful interactions.


How quickly does Avanafil work?

This salt tablet can start working in as little as 15 minutes for some men, though for others, it may take up to 30 minutes.

How long does the effect of Avanafil last?

The effects of it can last for up to 6 hours, allowing for flexibility and spontaneity in sexual activity.

Can I take Avanafil with alcohol?

While a small amount of alcohol may not interfere significantly, it’s best to avoid excessive drinking, as it can increase the risk of side effects.

Is Avanafil suitable for all men with ED?

Most men with ED can take this tablet, but it may not be suitable for everyone, especially those with certain health conditions. Consultation with a healthcare provider is essential.

Can I take Avanafil if I am taking other medications?

It’s important to discuss all medications you’re taking with your healthcare provider to ensure this salt is safe for you, particularly if you’re on nitrates or alpha-blockers.

Does Avanafil cure ED permanently?

This salt treats the symptoms of ED but does not cure the underlying condition. Continuous use is necessary to maintain the effects.

What should I do if Avanafil does not work?

Sometimes, adjusting the dose or the timing of the medication can help. However, if this salt consistently fails to work, consult your healthcare provider for advice and alternative treatments.

Can Avanafil be taken daily?

The salt is typically taken as needed and is not recommended for daily use unless specified by a healthcare provider.

Are there any food restrictions with Avanafil?

It can be taken with or without food. However, eating a high-fat meal may delay its onset of action.

What should I do in case of an overdose?

In the case of an overdose, immediate medical attention is necessary. The symptoms of an overdose may include severe side effects or prolonged erections.

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